UNAIDS estimates for the year 2012, 35.3 million persons are infected with the HIV worldwide and there were 2.3 million new infections and 1.6 million deaths that year. HIV, therefore, remains one of the major health threats. The cost associated with delivering antiretroviral drugs to people infected with HIV is overwhelming many organizations and public health systems worldwide.
State of the art: At present, combined antiretroviral treatment (ART) potently suppresses the virus to undetectable levels in blood. Nevertheless, virus persistence within different reservoirs and compartments presents a major barrier to eradicate the virus in patients undergoing long-term antiviral combination therapy.
Our research in HIV infection aims to: