Knowledge-based Mathematical Systems
Overview: The recent outbreaks of H1N1 (swine flu), H5N1 (bird flu), and H7N9 virus infections have underlined the impact of influenza A virus infections and have shown that influenza A virus is a major threat to human health. For example, the Mexican Institute for social security reported in 2009 a total of 117,626 people with influenza-like illness. CDC reports also showed that seasonal influenza infections account for annual hospitalization of 226,000 individuals in the USA
State of the art: The high degree of variability of the influenza virus due to mutations and secondary bacterial infections (Streptococcus pneumoniae and Staphylococcus aureus) are the leading cause of illness and death during influenza infection. Furthermore, the consequences of influenza virus infection are generally more severe in individuals over 65 years of age (the elderly).
Our research in Influenza Virus infection aims to: